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Discovering Human Genes

A portion of GRIA2 is shown here in an alignment of the genomes of several species, beneath a graph of the computer analysis. Peaks in the graph identify exons (regions that are expressed), separated by introns (non-coding regions). When a cell reads the gene to make a protein the introns are edited out.

BSCB researchers played a leading role in a multi-institution effort to identify novel human genes using computational and statistical methods. The project resulted in the identification of more than 300 new human genes and extensions of several hundred others.

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